I had swelling in my left knee, and my knee would colaspe on me at any time. After a visit to the knee doctor and xrays I was told it was age related cartilage wear. I refused shots and went with excerise to rebuild weak muscles. After several weeks my knee started to feel better, but still had some swelling and a little pain. I started taking Joint Astin and in just 24 hours the swelling and pain was gone. I take the perscribed 4 caps a day and have had no problems. I have also noted that I have more energy and feel better. I believe it helps in more areas than just joints. My wife now takes it for her sholders and hips. She is pain free now too. GREAT STUFF! I highly recommend it for people who have tried everything and still have pain.